Myostatin (uga dikenal minangka faktor diferensiasi pertumbuhan 8, disingkat peptida HMP (GDF-8) yaiku myokine, protein sing diasilake lan dibebasake dening myocytes sing tumindak ing sel otot kanggo nyegah pertumbuhan sel otot. Ing manungsa dikode dening gen MSTN. Myostatin minangka faktor diferensiasi pertumbuhan sing disekresi minangka anggota kulawarga protein beta TGF.
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