Name | AICAR |
CAS | 2627-69-2 |
MF | C9H14N4O5 |
MW | 258.23 |
Color | tan |
EINECS | 220-097-5 |
AICAR (2627-69-2) can activate AMP-activated protein kinas and promote ligand-independent activation of the insulin receptor. 1 Promotes skeletal muscle autophagy via activation of FoxO3a. 2 Controls smooth muscle cell hyperproliferation in vascular disease. 3 Induces osteogenic differentiation in mesenchymal stem cells. 4 Inhibits proinflammatory response in glial cells. 5 Cell permeable. |
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