Tesamorelin peptide (INN) (igoa fefaʻatauaʻiga Egrifta) o se ituaiga faʻapipiʻi o le hormone tuputupu aʻe-hormone-releasing hormone (GHRH) lea e faʻaaogaina i le togafitiga o lipodystrophy e fesoʻotaʻi ma HIV, faʻamaonia muamua i le 2010. E gaosia ma atiae e Theratechnologies, Inc .o Kanata. O le vailaʻau o se peptide synthetic e aofia uma 44 amino acids o le GHRH tagata faʻatasi ai ma le faʻaopoopoga o le trans-3-hexenoic acid group.

Tesamorelin peptide o se faʻamautu synthetic peptide analogue o le hypothalamic peptide, Growth Hormone Releasing Hormone (GHRH) ua faʻaalia mo le faʻaitiitia o le gaʻo tele o le manava i tagata mamaʻi pipisi i le HIV ma le lipodystrophy. Lipodystrophy o se maʻi gasegase e faʻaalia e le inisalini teteʻe, toe tufatufaina gaʻo, ma le hyperlipidemia e fesoʻotaʻi ma le antiretroviral therapy mo faʻamaʻi pipisi o le HIV.

Tesamorelin peptide o se faʻasologa o le hormone-releasing hormone (GHRH) analog lea ua faʻaalia e faʻateleina ai le hormone tuputupu aʻe ma le IGF-1. Tesamorelin o loʻo i ai nei le GH faʻamalolo sili ona lelei i luga o le maketi. O se peptide injectable lea e maua ai le tele o le gaosiga masani o le HGH (Human Growth Hormone). E fusifusia ma faʻaosofia tagata GHRH faʻafeiloaʻi e tutusa le malosi e pei o tatou lava GHRH masani. E leʻi faʻaalia e matua afaina ai isi hormones pituitary i totonu o le tino.

Gland Fa'aosofia: Pituitary Gland

AOGA O LE TESAMORELIN:

Faʻateleina gaosiga faʻanatura o le HGH (hormone tuputupu aʻe tagata)

Faʻateleina le IGF-1 (Insulin Growth Factor - 1) e aunoa ma le suia o le kulukose

Fa'aitiitia triglycerides

Fa'aitiitiga Visceral Adipose Tissue (VAT)

Fa'aiti'itia Carotid Intima Media Tele (cIMT)

Faʻaleleia le malamalama i tagata matutua i luga atu o le 60 tausaga.

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