Ka kakaretso, nts'etsopele ea lihlahisoa tse ncha tsa baeloji e tlameha ho feta (1) lipatlisiso tsa laboratori (phekolo ea tsela ea tlhahiso ea tlhahiso le ho theha litekanyetso tsa taolo ea boleng) (2) Lithuto tsa preclinical (lithuto tsa meriana, toxicological, pharmacodynamic le liteko tse ling tsa liphoofolo) (3) Lijo tsa bophelo bo botle. e tla fetisa tlhahlobo ea polokeho ea sehlahisoa se lekiloeng (4) Lithethefatsi li hloka ho feta methating e mehlano ea mosebetsi oa ho etsa lipatlisiso, joalo ka teko ea kliniki ea mohato oa I (ho hlahloba polokeho ea lithethefatsi le baithaopi ba phetseng hantle), teko ea kliniki ea phase II (small-scale Clinical). Pharmacodynamics Research), le teko ea kliniki ea mohato oa III (Lipatlisiso tse kholo tsa Clinical Pharmacodynamics Research), pele li ka amoheloa bakeng sa tlhahiso ea liteko. Kamora selemo se le seng sa tlhahiso ea liteko, moriana o tlameha ho tlaleha liphetho tsa botsitso ba boleng le liteko tse atolositsoeng tsa kliniki pele o etsa kopo ea tumello ea tlhahiso ea semmuso.