Hormone na haɓakar ɗan adam (hGH) shine hormone na endocrin da aka samar kuma aka adana shi ta glandan pituitary na gaba. hGH na iya haɓaka samuwar guringuntsi na articular da haɓakar guringuntsi na epiphyseal ta hanyar haɓakar hormone, wanda ke da mahimmanci ga haɓakar ɗan adam. Hakanan ana sarrafa shi ta wasu hormones da aka ɓoye ta hypothalamus. Idan rashi hGH zai iya haifar da rashin lafiyar jiki, yana haifar da gajeren tsayi. Ana ɓoye ɓoyewar hGH a cikin wurare dabam dabam ta hanyar bugun jini, kuma yana da wuya a gano HGH a cikin jini lokacin da yake cikin ɓoyayyen ɓoye. Yana karuwa a lokacin yunwa, motsa jiki da barci. Pituitary gland shine yake fara ɓoye hGH a ƙarshen wata na uku, kuma matakin hGH na tayin yana ƙaruwa sosai, amma matakin hGH na jarirai na cikakken lokaci yana da ƙasa, sa'an nan kuma matakin ɓoye yana ƙaruwa. matakin yara, kuma ya kai kololuwa a lokacin samartaka, kuma matakin ɓoyewar hGH a hankali yana raguwa a cikin manya sama da shekaru 30. Jama'a na yau da kullun suna buƙatar hGH don girma na tsayi, kuma yaran da ke da rashi hGH gajeru ne.
A cikin 1958, Raben ya fara ba da rahoton cewa ci gaban nama na marasa lafiya tare da dwarf hypophysial ya inganta sosai bayan allurar tsantsar pituitary ɗan adam. Duk da haka, a wancan lokacin, tushen hGH kawai shine glandon adenohypophysial na mutum don autopsy, kuma adadin hGH da za a iya amfani dashi don aikace-aikacen asibiti yana da iyaka. Kusan kawai 50 adenohypophysial glands sun isa don cire adadin HGH da ake bukata ta hanyar haƙuri ɗaya na shekara guda na jiyya. Sauran magungunan pituitary kuma na iya gurɓata saboda dabarun tsarkakewa. Tare da ci gaban kimiyya da fasaha, yanzu yana yiwuwa a samar da hormone girma na mutum ta hanyar injiniyan kwayoyin halitta. hGH da aka samar ta wannan hanya yana da tsari iri ɗaya kamar hGH a cikin jikin mutum tare da babban tsabta da ƙananan sakamako masu illa. Saboda yawan magungunan ƙwayoyi, ba kawai yara masu GHD na pituitary ba za a iya bi da su ba, amma har ma da maganin gajeren lokaci da wasu dalilai suka haifar.
Yin amfani da hormone girma don kula da ɗan gajeren tsayi, makasudin shine a ba da damar yaron ya kama, kula da girman girma na yau da kullum, samun dama ga balaga cikin sauri, kuma a ƙarshe ya kai tsayin girma. Ayyukan asibiti na dogon lokaci ya tabbatar da cewa hormone girma shine magani mai aminci da inganci, kuma farkon farkon jiyya, mafi kyawun tasirin magani.
Ko da yake ana kiran hormone girma kuma ana kiransa hormone, ya sha bamban da hormone na jima'i da glucocorticoid ta fuskar tushe, tsarin sinadarai, ilimin halittar jiki, ilimin harhada magunguna da sauran fannoni, kuma ba zai haifar da sakamako masu illa na hormone jima'i da glucocorticoid ba. Hormone girma shine hormone peptide wanda aka ɓoye ta glandan pituitary na baya na jikin mutum. Ya ƙunshi amino acid 191 kuma yana da nauyin kwayoyin 22KD. Hormone na girma yana taka rawar jiki ta hanyar motsa hanta da sauran kyallen takarda don samar da insulin-kamar girma factor (IGF-1), inganta haɓakar kasusuwa, inganta anabolism na jiki da haɓakar furotin, inganta lipolysis, da hana amfani da glucose. Kafin balaga, girma da haɓakar jikin ɗan adam ya fi dogara ne akan hormone girma da thyroxine, haɓakar balaga, haɓakar hormone synergistic hormone na jima'i, yana ƙara haɓaka saurin girma, idan jikin yaron ya rasa hormone girma, zai haifar da jinkirin girma. , a wannan lokacin, yana buƙatar ƙarin haɓakar hormone mai girma.
