Hoʻokaʻawale ʻia ia i nā lāʻau lapaʻau POLYPEPTIDE MEDICAL, peptide antibiotics, vaccines, peptides antimicrobial mahiʻai, peptides hānai, nā mea hoʻonaninani kemika i kēlā me kēia lā, SOYBEAN peptides no ka meaʻai, CORN peptides, yeast peptides, sea cucumber peptides.

Mai ka manaʻo hana, hiki ke hoʻokaʻawale ʻia i ka peptide antihypertensive, antioxidant peptide, cholesterol-lowering peptide, opioid active peptide, kiʻekiʻe F-value oligopeptide, meaʻai ʻono peptide a pēlā aku.

ʻO ka peptide ikaika, me ka meaʻai, hormone, enzyme inhibition, regulation of immune, antibacterial, antiviral, antioxidant he pilina pili loa. Hoʻokaʻawale ʻia nā peptide i: nā lāʻau peptide a me nā huahana olakino peptide. ʻO nā lāʻau lapaʻau peptide maʻamau ka nui o nā hormones peptide. Ua hoʻomohala ʻia ka hoʻomohala ʻana o nā lāʻau peptide ma nā ʻano like ʻole o ka pale ʻana a me ka mālama ʻana i nā maʻi, ʻoi aku hoʻi ma nā kahua aʻe.

Polypeptide anti-tumor

ʻO Tumorigenesis ka hopena o nā kumu he nui, akā ʻo ka hopena e pili ana i ka hoʻoponopono ʻana i ka ʻōlelo oncogene. Ua loaʻa ka nui o nā genes pili i ka tumo a me nā kumu hoʻoponopono i ka makahiki 2013. ʻO ka nānā ʻana i nā peptides e hoʻopaʻa pono i kēia mau genes a me nā kumu hoʻoponopono i lilo i wahi wela hou i ka ʻimi ʻana i nā lāʻau anticancer. No ka laʻana, ua hoʻohana ʻia ka somatostatin e mālama i nā ʻōpū endocrine o ka ʻōnaehana digestive; Ua loaʻa i ka poʻe noiʻi ʻAmelika kahi hexapeptide hiki ke kāohi nui i ka adenocarcinoma ma vivo; Ua ʻike nā kānaka ʻepekema Swiss i kahi octapeptide e hoʻoulu ai i ka apoptosis i loko o nā cell tumor.

ʻO ka polypeptide antiviral

Ma ka hoʻopaʻa ʻana i nā mea loaʻa kikoʻī ma nā cell host, hoʻopili nā maʻi i nā cell a hilinaʻi i kā lākou mau protease kikoʻī no ka hoʻoili ʻana i ka protein a me ka replication acid nucleic. No laila, hiki ke hoʻopaʻa ʻia nā peptides e hoʻopaʻa ʻia i nā mea hoʻokipa cell a i ʻole nā ​​​​wahi hana e like me nā protease viral mai ka waihona peptide no ka mālama antiviral. I ka makahiki 2013, ua nānā ʻo Canada, Italia a me nā ʻāina ʻē aʻe i nā peptides liʻiliʻi me ka pale ʻana i ka maʻi mai ka waihona peptide, a ua komo kekahi o lākou i ke kahua o nā hoʻokolohua lapaʻau. I Iune 2004, ka Institute of Microbiology, Chinese Academy of Sciences i hōʻike i ke kuhikuhi koʻikoʻi o ka ʻike hana hou i hana ʻia e ka Institute of Microbiology, Chinese Academy of Science, "Research on the mechanism of SARS-CoV cell fusion and Fusion inhibitors", i hana pū ʻia e ka Institute of Microbiology, Chinese Academy of Science a me ka Center for Modern Virology, Life Science, Wuhan University, ua holomua nui. Ua hōʻike ʻia nā hoʻokolohua hiki i ka peptide HR2 i hoʻolālā ʻia ke pale pono i ka maʻi o nā cell moʻomeheu e ka maʻi maʻi SARS, a ʻo ka hoʻopaʻa paʻa pono ʻana aia ma ke ʻano o nā nmoles. Ua hana nui ʻia ka holomua ma ka hoʻokolohua hoʻokolohua hoʻopaʻa ʻana i ka maʻi viral o ka synthesized a hōʻike ʻia HR1 peptide a me nā hoʻokolohua in vitro paʻa o HR1 a me HR2. ʻO nā lāʻau peptide i kūkulu ʻia e pale i ka hui ʻana o ka maʻi SARS hiki ke pale i ka maʻi o ka maʻi a, i ka hihia o nā maʻi maʻi, pale i ka hoʻolaha hou ʻana o ka maʻi i loko o ke kino. Loaʻa i ka lāʻau polypeptide nā hana pale a me ka therapeutic. Ua hana nā mea noiʻi ma ka Cell Engineering Research Center o ka ʻEhā Military Medical University i ʻeiwa peptides i hiki ke pale pono a pale i ka hoʻouka ʻana o ka maʻi SARS i loko o nā cell.

Hoʻohālike nā cytokines i nā peptides

ʻO ka hoʻohana ʻana i nā mea hoʻokipa no nā cytokines i ʻike ʻia e nānā i ka cytokine mimics mai nā hale waihona puke peptide ua lilo i wahi wela noiʻi ma 2011. ʻO ka nānā ʻana e nā poʻe ma waho erythropoietin, hoʻonui nā kānaka i ka platelet hormone, growth hormone, nerve growth factor a me nā ʻano mea ulu like ʻole interleukin - 1 simulation peptide, ʻokoʻa ka simulation o ka peptide amino acid sequence a me kāna helu cell like, ke kaʻina o nā amino acids akā aia ka hana o nā cytokines, a loaʻa iā ia nā pōmaikaʻi o ka liʻiliʻi.kaumaha molekala. I ka makahiki 2013, aia kēia mau cytokine mimicking peptides ma lalo o ka noiʻi preclinical a i ʻole ka hoʻokolohua lapaʻau.

ʻO ka peptide hana antibacterial

Ke hoʻoulu ʻia nā iniseti e ka kaiapuni o waho, hana ʻia ka nui o nā peptides cationic me ka hana antibacterial. Ma 2013, ʻoi aku ma mua o 100 mau ʻano peptides antimicrobial i hoʻopaʻa ʻia. Ua hōʻoia ʻia nā hoʻokolohua in vitro a me in vivo he nui nā peptides antimicrobial ʻaʻole wale ka ikaika antibacterial a me ka bactericidal ikaika, akā hiki nō ke pepehi i nā cell tumor.

ʻO ka lāʻau lapaʻau peptide

ʻO nā lāʻau lapaʻau peptide a me ka waika nucleic kekahi o nā mea koʻikoʻi i ke kahua o ka noiʻi ʻana i ka lāʻau lapaʻau ma 2013. Ua hana ʻia ka nui o ka noiʻi a me ka hoʻomohala ʻana o nā maʻi peptide viral i ka honua ma 2013. No ka laʻana, ma 1999, ua paʻi ʻo NIH i ka nā hopena hoʻokolohua lapaʻau o ʻelua ʻano o ka maʻi maʻi peptide maʻi HIV-I ma luna o nā kumuhana kanaka; Ua hoʻopaʻa ʻia kahi polypeptide mai ka protein membrane waho E2 o ka maʻi hepatitis C (HCV), hiki ke hoʻoulu i ke kino e hana i nā antibodies pale. Ke hoʻomohala nei ʻo ʻAmelika Hui Pū ʻIa i ka maʻi malaria polyvalent antigen polypeptide vaccine; Ua komo ka lāʻau lapaʻau peptide papillomavirus kanaka no ka maʻi maʻi ʻāʻī i ka pae II i nā hoʻokolohua lapaʻau. Ua hana ʻo Kina i nā hana he nui i ka noiʻi ʻana i nā ʻano lāʻau lapaʻau polypeptide.

ʻO nā peptide no ka ʻike

ʻO ka hoʻohana nui ʻana o nā peptides i nā reagents diagnostic e like me nā antigens, nā antibodies e ʻike i nā meaola pathogenic pili. ʻOi aku ka kikoʻī o nā antigens polypeptide ma mua o nā microbial maoli a i ʻole nā ​​​​antigens protein parasitic a ua maʻalahi ka hoʻomākaukau. ʻO nā mea hoʻopalekana ʻike antibody i hui pū ʻia me nā antigens polypeptide i ka makahiki 2013: A, B, C, G ate maʻi maʻi, HIV, cytomegalovirus kanaka, herpes simplex virus, rubella virus, Treponema pallidum, cysticercosis, trypanosoma, Lyme maʻi a me ka rheumatoid detection reagents. ʻO ka hapa nui o nā antigens peptide i hoʻohana ʻia i loaʻa mai ka protein maoli o ke kino pathogenic pili, a ʻo kekahi mau peptides hou loa i loaʻa mai ka waihona peptide.