Ko te Semalutide, he glucagon rite ki te peptide (GLP-1) agonist kaiwhakawhiwhi, kua whakaaetia mo te maimoatanga o te mate huka momo 2. I whakawhanakehia a Somaglutide e Novo Nordisk i 2012 hei whakakapi mo te wa roa ki te Liraglutide. Ka whakatauritea ki te Liraglutide me etahi atu rongoa mo te mate huka, ko tetahi o nga painga o te Somaglutide he roa te waa mahi, no reira ka nui te werohanga i te wiki. I te Hakihea 2017, ka whakaaetia e te US Food and Drug Administration (FDA) te momo werohanga o te somalutide. I kitea e te whakamatautau haumanu o te wahanga II o mua ko te Somaglutide i whakaiti i te taumaha o nga turoro mate huka momo 2 me nga taangata momo, a ko te mate taimaha i kiia na te whakahekenga o te kaha o te kai na te whakahekenga o te hiahia.