Ko te Tesamorelin peptide (INN) (ingoa hokohoko Egrifta) he ahua hangai o te tipu-hormone-releasing hormone (GHRH) e whakamahia ana i roto i te maimoatanga o te lipodystrophy e pa ana ki te HIV, i whakaaetia i te tuatahi i te 2010. He mea whakaputa me te whakawhanakehia e Theratechnologies, Inc .o Kanata. Ko te tarukino he peptide waihanga kei roto katoa nga waikawa amino 44 o te GHRH tangata me te taapiri o te roopu waikawa trans-3-hexenoic.

Ko te peptide Tesamorelin he peptide synthetic o te peptide hypothalamic, Growth Hormone Releasing Hormone (GHRH) i tohuhia mo te whakaheke i te ngako o te puku i roto i nga turoro kua pangia e te HIV me te lipodystrophy. Ko te Lipodystrophy he mate e pa ana ki te mate o te insulin, te tohatoha ngako, me te hyperlipidemia e pa ana ki te rongoa antiretroviral mo te mate HIV.

Ko te peptide Tesamorelin he tairitenga o te hormone-releasing hormone (GHRH) kua whakaatuhia ki te whakanui ake i te taiaki tupu me te IGF-1 taumata. Ko Tesamorelin te wa tino whai hua GH tuku homoni i runga i te maakete. He peptide injectable e whakaputa ana i te hanga nui ake o te HGH (Human Growth Hormone). Ka herea, ka whakaihiihi i nga kaiwhakawhiwhi GHRH tangata he rite te kaha ki to tatou ake GHRH taiao. Kaore ano kia tino pa ki etahi atu homoni pituitary i roto i te tinana.

Whakatairanga i te repe: Pituitary Gland

NGA PAINGA O TESAMORELIN:

Ka whakanui ake i nga hua o te HGH (hormone tipu tangata)

Ka whakanui ake i te IGF-1 (Tauturu Whakanui Insulin - 1) me te kore e whakarereke i nga tawhā huka

Kua whakahekehia te triglycerides

Ko te Tissue Visceral Adipose Whakaiti (VAT)

Whakaitihia te Rahi Paapāho Carotid Intima (cIMT)

He pai ake te mohiotanga i roto i nga pakeke neke atu i te 60 tau.

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