2021 ndi chaka cha 100 cha kupezeka kwa insulin. Kupezeka kwa insulin sikungosintha tsogolo la odwala omwe ali ndi matenda ashuga omwe anamwalira atawazindikira, komanso kulimbikitsa kumvetsetsa kwa anthu za protein biosynthesis, mawonekedwe a crystal, matenda a autoimmune ndi mankhwala olondola. Pazaka 100 zapitazi, pakhala Mphotho 4 za Nobel pakufufuza za insulin. Tsopano, kupyolera mu ndemanga yomwe yafalitsidwa posachedwapa mu Natural Medicine ndi Carmella Evans-Molina ndi ena, tikuwunikira mbiri yakale ya insulini ndi zovuta zomwe timakumana nazo m'tsogolomu.