Chifukwa kuchokera ku lingaliro la mapuloteni, selo lililonse m'thupi ndi zigawo zonse zofunika zimakhala ndi mapuloteni. Mapuloteni amawerengera 16% ~ 20% ya kulemera kwa thupi la munthu. Pali mitundu yambiri ya mapuloteni m'thupi la munthu, omwe ali ndi katundu ndi ntchito zosiyanasiyana, koma onsewa ali ndi mitundu 20 ya ma amino acid mosiyanasiyana, ndipo amasinthidwa nthawi zonse ndikusinthidwa m'thupi.

Ma amino acid 20 awa m'thupi la munthu amatha kuphatikizidwa momasuka kukhala ma peptides 2,020, omwe ndi ochuluka kwambiri. Malinga ndi malingaliro oyambira kuti kapangidwe kachilengedwe kamapangitsa ntchito, mfundo ya peptide iliyonse yogwira ndiyovuta kwambiri. Monga antibacterial anti-inflammatory peptide, immune regulatory peptide mu thymosin.

Peptide ya antibacterial anti-inflammatory: peptide anti-inflammatory (C-L) → mtengo wabwino → zochita za cell membrane → mu tizilombo toyambitsa matenda (monga Escherichia coli) kubowola nembanemba yama cell → kutayikira kwazinthu zamkati mwa cell → kufa kwa mabakiteriya, ndiko kuti, kupha mabakiteriya; Nthawi yomweyo, imatha kuchepetsa endotoxin → kuchepetsa kutupa komwe kumachitika chifukwa cha LPS.

Thymosin pakati pa ma immunomodulatory peptides amatha kupititsa patsogolo chitetezo chamthupi poyambitsa kukula ndi kukhwima kwa T lymphocyte subsets, kukulitsa luso la phagocytosis la macrophages ndikuwonjezera kuchuluka kwa mawu a interleukin. Ng'ombe ya thymosin, monga momwe timatchulira nthawi zambiri, imagwira ntchito kwambiri pa T-lymphocyte kuti ipititse patsogolo chitetezo chamthupi chamthupi ndikuwonjezera kukana matenda.

Il-6 ndi chinthu cha pleiotropic, chomwe chimatha kuyendetsa kukula ndi kusiyanitsa kwa maselo osiyanasiyana, kuwongolera chitetezo cha mthupi, kuyankha kwapang'onopang'ono ndi ntchito ya hematopoietic, ndikugwira ntchito yofunikira pakuyankha kwa chitetezo cha mthupi.

LTA ikhoza kupititsa patsogolo chitetezo cha mthupi mwa kumanga TLR4 / MD2 zovuta → kutsegula kwa NF-кB njira yowonetsera → phagocytosis ntchito ya ↑T lymphocytes ndi macrophages ndi chitetezo cha mthupi (monga TNF-α, IL-6, IL-1β, etc.).

Anthu osiyanasiyana zokhudza thupi boma si chimodzimodzi, zidzachititsa zotsatira kutenga peptide si chimodzimodzi, monga kudya chakudya chomwecho anthu ena amadya mafuta ambiri, anthu ena sadya mafuta.

Ponena za msinkhu, zotsatira za okalamba kaŵirikaŵiri zimakhala zabwino kuposa achichepere; Kuchokera ku thanzi, odwala amadya peptide effect. Munthu wathanzi. Pankhani ya kutopa, anthu otopa amachita bwino kuposa ena; Anthu omwe adachitidwa opaleshoni adachita bwino ndi ma peptides kuposa omwe sanachite opaleshoni ...

Chifukwa ma peptides ali ndi zakudya zambiri zopatsa thanzi, zosavuta kuyamwa, kuchepetsa kulemedwa kwa m'mimba, kulimbikitsa machiritso a mabala komanso mawonekedwe odana ndi kutopa, ndiye kuti ndizofanana ndi mankhwala oyenera, anthu akakhala m'thupi, amafunikira ma peptides osiyanasiyana. ntchito zowonjezera.

Ndi chitukuko cha anthu, anthu amakono akukumana ndi mavuto ambiri okhudzana ndi kuchepetsa ma peptides. Mwachitsanzo, feteleza wamankhwala ndi mankhwala ophera tizilombo amachotsa ma enzyme omwe amawononga mapuloteni m'zakudya ndikuchepetsa ma enzymes akunja. Malo amakono chifukwa cha kuipitsidwa kwa mpweya, kuipitsidwa kwa madzi ndi nthaka, kutayika kapena kutsekedwa kwa ma enzymes m'thupi la munthu, mphamvu ya thupi la munthu kuwononga mapuloteni imafooka, chimbudzi ndi kuwonongeka sikungathe kuchitidwa mwachizolowezi, mwayi wopeza ma peptides ndi kuchepetsedwa, kotero thupi la munthu likusowa ma peptides; Ma radiation amakono amapangitsa kuti chitetezo cha mthupi cha munthu chikhale chochepa, kukhoza kugaya ndi kuwononga mapuloteni kumaletsedwa, njira yoyamwitsa sungatenge mapuloteni bwino, ndipo mwayi wopeza ma peptide umachepetsedwa.

Kuperewera kwa peptide kwakhala vuto wamba chifukwa cha kuwonongeka kwakukulu komanso kutayika kwa ma peptide m'thupi la munthu. Pamene mphamvu ya thupi la munthu kupanga ma peptide imafooka kwambiri, thupi la munthu silingathe kudzaza ma peptides panthawi yake, kotero ndikofunikira kumwa mankhwala kuti akwaniritse zosowa za thupi la munthu.