Auxin atha kugwiritsidwa ntchito pochiza kuchepa kwachitukuko komwe kumachitika chifukwa cha kuchepa kwa timadzi tambiri.

Hormone ya kukula, yomwe imadziwikanso kuti human growth hormone (hgh), ndi mahomoni a peptide omwe amaletsedwa kugwiritsidwa ntchito pamasewera ndipo amagwiritsidwa ntchito pochiza dwarfism. Lili ndi zotsatira za kupanga ndi kagayidwe kachakudya zomwe zimachulukitsa minofu, zimalimbikitsa kukula kwa mafupa mwa ana ndi achinyamata, komanso kulimbitsa mitsempha ndi ziwalo zamkati. Othamanga amagwiritsa ntchito GH mosaloledwa makamaka kuti apange minofu ndi mphamvu kuti apindule nawo mpikisano.

Malinga ndi zolembazo, jekeseni wa subcutaneous kapena intramuscular ndi wothandiza mofanana, ndipo jekeseni wa subcutaneous nthawi zambiri amabweretsa kuchuluka kwa seramu GH kuposa jekeseni wa intramuscular, koma ndende ya IGF-1 ndi yofanana. Mayamwidwe a GH nthawi zambiri amakhala pang'onopang'ono, ndipo kuchuluka kwa GH m'madzi a m'magazi kumakwera kwambiri 3-5 h pambuyo pa kuwongolera, ndi theka la moyo wa 2-3 h. GH imatsukidwa kudzera m'chiwindi ndi impso, mofulumira kwa akuluakulu kusiyana ndi ana, ndipo kuchotsa mwachindunji kwa unmetabolized GH mu mkodzo kumakhala kochepa. Kuchiza kukula pang'onopang'ono komanso kutentha kwambiri kwa ana omwe ali ndi vuto la kuchepa kwa mahomoni, kulephera kwaimpso, ndi Turner syndrome.

Chifukwa chiyani kukula kwa mahomoni amunthu kumachepa ndi zaka:

Kudzimva nokha kumazungulira kuchitapo kanthu. Pamene IGF-l imachepa m'thupi, zizindikiro zimatumizidwa ku chithokomiro cha pituitary kuti chitulutse hGH yambiri, ndipo izi zimachepetsedwa ndi msinkhu.