Ubuvuzi bukoreshwa cyane mubuvuzi bwa hormone yo gukura ni fenol, cresol nibindi. Fenol ni imiti isanzwe ikingira imiti. Ubushakashatsi bwakozwe n'ikigo cyo muri Amerika gishinzwe kurengera ibidukikije (EPA) bwerekanye ko guhura na fenol bishobora gutera akabariro gukura kw'inda. Habayeho ibibazo byo gukoresha ibitaro gukoresha imiti yica udukoko twa fenolike bigatuma habaho indwara ya hypobilirubinemia y’impinja ndetse n’impfu zimwe na zimwe, bityo rero fenol ifatwa nkuburozi ku bana cyangwa ku nda.

Kubera uburozi bwa fenol, FDA, EU n'Ubushinwa byagenzuye byimazeyo imipaka yo hejuru yo kongeramo imiti igabanya ubukana. FDA iteganya ko kwibumbira hamwe kwa fenolike bigomba kugenzurwa muri 0.3%, ariko FDA isobanura kandi ko hagaragaye ingaruka mbi zikomeye ku barwayi bamwe na bamwe ndetse no mu gihe byemewe, kandi hagomba kwirindwa gukoresha igihe kirekire. Gukomeza gufata dosiye nke zemewe nazo zigomba kwirindwa muminsi irenze 120. Nukuvuga ko, nubwo kwibumbira hamwe kwa fenoline yongewe mumisemburo yo gukura ari bike cyane, ingaruka mbi zayo akenshi zibaho nyuma yo kuyikoresha igihe kirekire, ndetse nindwara zitera indwara zishobora kuboneka ahantu hose. N'ubundi kandi, imiti igabanya ubukana ni bacteriostatike n'uburozi bwayo, kandi niba uburozi buri hasi cyane, intego ya bacteriostatike ntabwo ikora neza.

Bitewe nubuhanga buhanitse bwibikoresho byamazi akura, benshi mubakora imisemburo ya hormone yo gukura barashobora kongeramo imiti igabanya ubukana kugirango imisemburo ikura itangirika bitewe nubuhanga buke bwo gukora, ariko gutera inshinge igihe kirekire bizana ingaruka mbi zuburozi sisitemu yo hagati yabana, umwijima, impyiko nizindi ngingo z'umubiri. Kubwibyo rero, kubarwayi bafite gukoresha igihe kirekire imisemburo ikura, imisemburo yo gukura idafite imiti igabanya ubukana igomba gutoranywa uko bishoboka kwose, kugirango birinde ingaruka mbi ziterwa nuburozi no gukoresha igihe kirekire kubana neza.