Uburyo bwo gukora imisemburo ya steroid

 KNOWLEDGE    |      2023-03-28

Ibisobanuro byerekana ibisekuru. Imisemburo ya Steroide ifite uburemere buke bwa molekile kandi irashobora gushonga. Barashobora kwinjiza selile mugukwirakwiza cyangwa gutwara ibintu. Nyuma yo kwinjira mu ngirabuzimafatizo, imisemburo ya steroid ihuza reseptor muri cytosol kugirango ikore imisemburo-ya reseptor, ishobora guhinduranya allosteric binyuze muri membrane ya kirimbuzi mubushyuhe bukwiye kandi Ca2 + ikabigiramo uruhare.

Nyuma yo kwinjira muri nucleus, imisemburo ihuza reseptor muri nucleus kugirango igire urwego rugoye. Uru ruganda ruhuza imbuga zihariye muri chromatine itari amateka, itangiza cyangwa ikabuza inzira yo kwandukura ADN kururu rubuga, hanyuma igateza imbere cyangwa ikabuza gushiraho mRNA. Nkigisubizo, itera cyangwa igabanya synthesis ya proteine ​​zimwe na zimwe (cyane cyane enzymes) kugirango igere ku ngaruka zayo. Molekile imwe ya hormone irashobora kubyara molekile ibihumbi n'ibihumbi bya poroteyine, bityo bikagera ku mikorere yagutse ya hormone.

Igisubizo cya Hormone Mugihe cyibikorwa byimitsi, urwego rwimisemburo itandukanye, cyane cyane itera imbaraga zo gutanga ingufu, ihinduka kurwego rutandukanye kandi ikagira ingaruka kumiterere ya metabolike yumubiri nurwego rwimikorere yingingo zitandukanye. Gupima urwego rwa hormone zimwe na zimwe mugihe na nyuma yo gukora siporo no kuzigereranya nindangagaciro zituje byitwa igisubizo cya hormone kumyitozo ngororamubiri.

HORMONES yihuse, NKUKO EPINEPHRINE, NOrepINEPHRINE, CORTISOL, na ADRENOCORTICOTROPIN, BISANZWE CYANE MURI plasma AKANYA NYUMA YIMYITOZO hanyuma ikagira impinga mugihe gito.

Hagati aho imisemburo ikora nka aldosterone, thyroxine, na pressor, izamuka gahoro gahoro muri plasma nyuma yimyitozo ngororangingo, igera ku mpinga mu minota mike.

Buhoro buhoro imisemburo yo gusubiza, nka hormone yo gukura, glucagon, calcitonine na insuline, ntabwo bihinduka ako kanya nyuma yo gutangira imyitozo, ariko byiyongera buhoro buhoro nyuma ya 30 kugeza 40min y'imyitozo ngororamubiri kandi bigera ku mpinga mugihe cyakera.