Nk’uko bigaragara mu mpapuro nshya zasohotse mu bumenyi bwa shimi, prodrug yo mu kanwa yakozwe nitsinda ry’abahanga bayobowe na Porofeseri Wang Binghe mu ishami ry’ubutabire muri kaminuza ya Leta ya Jeworujiya irashobora gutanga monoxide ya karubone kugira ngo ikomeretsa impyiko zikabije.

Nubwo gaze ya karubone (CO) ifite uburozi muri dosiye nini, abahanga basanze ishobora kugira ingaruka nziza mukugabanya umuriro no kurinda selile kwangirika. Ubushakashatsi bwakozwe mbere bwerekanye ko CO igira ingaruka zo kurinda kwangirika kwingingo nkimpyiko, ibihaha, gastrointestinal tract numwijima. Mu myaka itanu ishize, Wang na bagenzi be barimo gukora uko bashoboye kugira ngo hategurwe uburyo bwizewe bwo kugeza CO ku barwayi b’abantu binyuze mu miti idakora ya prodrugs igomba gukorerwa imiti mu mubiri mbere yo kurekura imiti ikora imiti.