Peptide inoshanda sei? Sei uchida peptides?

 KNOWLEDGE    |      2023-03-28

Nekuti kubva papfungwa yeprotein, sero rega rega mumuviri uye zvese zvakakosha zvinoriumba zvine mapuroteni anobatanidzwa. Mapuroteni anoita 16% ~ 20% yehuremu hwemuviri wemunhu. Kune marudzi akawanda emapuroteni mumuviri wemunhu, ane zvimiro uye mabasa akasiyana, asi ese anoumbwa nemhando makumi maviri eAmino acid muzvikamu zvakasiyana, uye anogara achigadziriswa uye achivandudzwa mumuviri.

Aya makumi maviri amino acids mumuviri wemunhu anogona kusanganiswa zvakasununguka kuita 2,020 peptides, inova nhamba huru kwazvo. Zvinoenderana nemaonero ekutanga ekuti biological chimiro chinotemesa basa, misimboti yekuita yepeptide yega yega inoshanda yakaoma. Zvakadai se antibacterial anti-inflammatory peptide, immune regulatory peptide mu thymosin.


Antibacterial anti-inflammatory peptide: antibacterial anti-inflammatory peptide (C-L)→ positive charge → kuita kwebacteria cell membrane → mupathogen (seEscherichia coli) cell membrane drilling → intracellular material leakage → kufa kwebhakitiriya, kureva, kuuraya utachiona; Panguva imwecheteyo, inogona kuderedza endotoxin → kuderedza kuzvimba kunokonzerwa neLPS.

Thymosin pakati pe immunomodulatory peptides inogona kukwidziridza mashandiro emuviri nekusimudzira kukura uye kukura kweT lymphocyte subsets, kuwedzera phagocytosis kugona kwema macrophages uye kuwedzera kutaura kweinterleukin. Mhuru thymosin, sezvatinowanzoidaidza kuti, inonyanya kuita paT-lymphocyte system kusimudzira masero edziviriro emuviri uye kuwedzera kurwisa chirwere.

Il-6 inonzi pleiotropic factor, iyo inogona kugadzirisa kukura uye kusiyanisa kwemasero akasiyana-siyana, kugadzirisa maitiro ekudzivirira zvirwere, acute phase response uye hematopoietic function, uye inotora basa rinokosha mukurwisana nehutachiona hwehutachiona.


LTA inogona kuwedzera basa rekudzivirira muviri nekusunga TLR4 / MD2 yakaoma → kushandiswa kweNF-кB chiratidzo chenzira → phagocytosis basa re ↑T lymphocytes uye macrophages uye zvinhu zvekudzivirira (zvakadai seTNF-α, IL-6, IL-1β, nezvimwewo).

Vanhu vakasiyana physiological mamiriro haana kufanana, kuchaita kuti mhedzisiro yekutora peptide haina kufanana, sekudya chikafu chimwechete vamwe vanhu vanodya mafuta akawanda, vamwe vanhu havadyi mafuta.


Maererano nezera, migumisiro yevakwegura inowanzova nani pane vaduku; Kubva pane hutano, vanhu vanorwara vanodya peptide maitiro. Munhu ane hutano. Panyaya yekuneta, vanhu vakaneta vanoita zviri nani pane vamwe; Vanhu vakavhiyiwa vakaita zvirinani nepeptides pane vanhu vasina kuvhiyiwa...


Nekuti peptides ine hutano hwepamusoro, huri nyore kutora, kuderedza mutoro wekugaya, kukurudzira kupora kwemaronda uye anti-kuneta hunhu, saka zvakafanana nemushonga chaiwo, kana vanhu vari mumamiriro emuviri, vanoda mapeptides ane akasiyana. mabasa ekuzadzisa.

Nekuvandudzwa kwevanhu, vanhu vemazuva ano vanotarisana nematambudziko akawanda ane chokuita nekuderedza peptides. Semuyenzaniso, mafetereza emakemikari nemishonga yezvipembenene zvinobvisa maenzayimu anoshatisa mapuroteni muchikafu uye kuderedza maenzayimu ekunze. Nzvimbo yemazuva ano nekuda kwekusvibiswa kwemhepo, kusvibiswa kwemvura uye ivhu, kurasikirwa kana kusashanda kwema enzymes mumuviri wemunhu, kugona kwemuviri wemunhu kusvibisa mapuroteni kunopera simba, kugaya uye kuparara hakugone kuitwa zvakajairwa, mukana wekuwana peptides. yakaderedzwa, saka muviri wemunhu hauna peptides; Mwaranzi yemazuva ano inoita kuti immune system yemunhu ive yakadzikira, kugona kugaya nekudzikisa mapuroteni kunodzivirirwa, iyo absorption system haigone kutora mapuroteni kazhinji, uye mukana wekuwana peptides wakaderedzwa.


Kushaikwa kwePeptide rave dambudziko rakajairika nekuda kwehuwandu hukuru hwekukuvadza uye kurasikirwa kwepeptides mumuviri wemunhu. Kana kugona kwemuviri wemunhu kugadzira peptides kwakadzikira zvakanyanya, muviri wemunhu haugone kuzadza peptides nenguva, saka zvinodikanwa kutora mishonga kuti isangane nezvinodiwa nemuviri wemunhu.