Waxay inta badan u qaybsantaa dawooyinka POLYPEPTIDE, dawooyinka peptide antibiyootiga, tallaalada, peptides-ka antimicrobial beeralayda, peptides quudinta, kiimikooyinka maalinlaha ah ee la isku qurxiyo, peptides SOYBEAN ee cuntada, peptides GUDAHA, peptides khamiirka, peptides qajaar badda.

Marka laga eego aragtida shaqada, waxaa loo qaybin karaa peptide antihypertensive, peptide antioxidant, peptide hoos u dhigista kolesteroolka, peptide firfircoon ee opioid, oligopeptide F-qiimaha sare, peptide dhadhanka cuntada iyo wixii la mid ah.

Peptide firfircoon, oo leh nafaqo, hoormoon, xakameynta enzyme, xakamaynta difaaca, bakteeriyada, fayraska, antioxidant waxay leedahay xiriir aad u dhow. Peptides guud ahaan waxa loo qaybiyaa: dawooyinka peptide iyo alaabta caafimaadka peptide. Daawooyinka peptide-ka dhaqameedku waa hormoonnada peptide. Horumarinta daawooyinka peptide ayaa lagu sameeyay qaybo kala duwan oo ka hortagga iyo xakamaynta cudurrada, gaar ahaan qaybaha soo socda.

Ka hortagga burada polypeptide

Tumorigenesis waa natiijada arrimo badan, laakiin ugu dambeyntii waxay ku lug leedahay nidaaminta muujinta oncogene. Hido-sideyaal badan oo buro la xidhiidha iyo arrimo sharciya ayaa la helay 2013. Baadhista peptides ee si gaar ah ugu xidhan hidde-sidayaashan iyo qodobbada sharciyaynta ayaa noqday meel cusub oo lagu raadinayo dawooyinka kansarka. Tusaale ahaan, somatostatin ayaa loo isticmaalay in lagu daweeyo burooyinka endocrine ee habka dheef-shiidka; Cilmi-baarayaasha Maraykanku waxay heleen hexapeptide oo si weyn u xakameyn kara adenocarcinoma ee vivo; Saynisyahano Swiss ah ayaa helay octapeptide kaas oo keena apoptosis unugyada burooyinka.

Polypeptide ka hortagga fayraska

Iyada oo lagu xidho reseptors gaar ah oo ku saabsan unugyada martida loo yahay, fayrasyadu waxay xoojiyaan unugyada waxayna ku tiirsan yihiin borotiinka gaarka ah ee habaynta borotiinka iyo soo celinta aashitada nucleic. Sidaa darteed, peptides-ku-xidhka marti-gelinta unugyada unugyada ama goobaha firfircoon sida fayraska proteases ayaa laga baari karaa maktabadda peptide si loogu daaweeyo fayraska. 2013, Kanada, Talyaaniga iyo dalal kale ayaa baadhay peptides yar yar oo badan oo leh caabbinta cudurrada ee maktabadda peptide, iyo qaar ka mid ah ayaa soo galay marxaladda tijaabooyinka caafimaad. In June 2004, Institute of Microbiology, Academy Shiinaha ee Sayniska ayaa sheegay in jihada muhiimka ah ee mashruuca hal-abuurnimo aqoon by Institute of Microbiology, Akadeemiyada Shiinaha ee Sayniska, "Cilmi ku saabsan habka of SARS-CoV fusion cell iyo Fusion inhibitors", kaas oo ay si wada jir ah u fulinayeen machadka Microbiology, Akadeemiyada Sayniska ee Shiinaha iyo Xarunta Cilmi-nafsiga Casriga ah, Sayniska Nolosha, Jaamacadda Wuhan, ayaa ku tallaabsatay horumar la taaban karo. Tijaabooyinku waxay caddeeyeen in peptide-ka HR2 ee nashqadeeyay uu si wax ku ool ah u joojin karo caabuqa unugyada dhaqan ee fayraska SARS, iyo feejignaanta wax-ku-oolka ah ee xannibaadda waxay ku jirtaa fiirsashada dhowr nmoles. Horumar muhiim ah ayaa sidoo kale laga sameeyay tijaabooyinka ka hortagga caabuqa fayraska ee la soo saaray oo la muujiyey HR1 peptide iyo tijaabooyinka isku xidhka in vitro ee HR1 iyo HR2. Dawooyinka peptide ee loo sameeyay si looga hortago isku dhafka fayraska SARS waxay ka hortagi karaan infekshanka fayraska, haddii ay dhacdo bukaannada qaba, waxay ka hortagaan faafitaanka fayraska ee jirka. Daawada polypeptide waxay leedahay hawlo ka hortag iyo daweyn labadaba. Cilmi-baarayaasha Xarunta Cilmi-baarista Injineerinka Unug ee Jaamacadda Caafimaadka Millateriga ee Afraad waxay soo saareen sagaal peptides kuwaas oo si wax ku ool ah uga hortagi kara oo joojin kara duulaanka fayraska SARS ee unugyada.

Cytokines waxay la mid yihiin peptides

Isticmaalka reseptors ee cytokines loo yaqaan si loo baadho cytokine mimics ka maktabadaha peptide waxay noqotay goob cilmi baaris ah 2011. Baadhitaanka dadka dibadda erythropoietin, dadku waxay kor u qaadaan hormoonka platelet, hormoonka koritaanka, factor koritaanka dareemayaasha iyo in noocyo kala duwan oo arrimo koritaanka sida interleukin - 1 jilitaanka peptide, jilitaanka isku xigxiga amino acid peptide iyo unugga u dhigma waa ka duwan yahay, isku xigxiga ee acids amino laakiin waxa uu leeyahay waxqabadka cytokines, oo uu leeyahay faa'iidooyinka yar yar.miisaanka kelli. Sannadkii 2013-kii, kuwan cytokine-ka-yeelka ah ee peptides-ka waxay ku hoos jiraan baaritaan caafimaad ama caafimaad.

Antibakteeriyada firfircoon ee peptide

Marka cayayaanka ay kiciyaan deegaanka dibadda, tiro badan oo peptides cationic ah oo leh firfircoonida bakteeriyada ayaa la soo saaraa. Sannadkii 2013, in ka badan 100 nooc oo peptides-ka lidka ku ah jeermiska ayaa la baadhay. Tijaabooyinka gudaha vitro iyo in vivo waxay xaqiijiyeen in badan oo ka mid ah peptides antimicrobial ma leeyihiin oo kaliya awood bakteeriyada iyo bakteeriyada, laakiin sidoo kale waxay dili karaan unugyada burooyinka.

Tallaalka Peptide

Tallaalka Peptide iyo tallaalada nucleic acid waxay ahaayeen mid ka mid ah dhinacyada ugu muhiimsan ee cilmi-baarista tallaalka ee 2013. Cilmi-baaris badan iyo horumarinta tallaallada peptide viral ayaa lagu sameeyay adduunka 2013. Tusaale ahaan, 1999, NIH ayaa daabacday Natiijooyinka tijaabada caafimaad ee laba nooc oo ah tallaalada peptide fayraska HIV-I ee maadooyinka aadanaha; Polypeptide ayaa laga baadhay borotiinka xuubka sare E2 ee fayraska cagaarshow C (HCV), kaas oo kicin kara jidhka si uu u soo saaro unugyada difaaca. Maraykanku waxa uu samaynayaa tallaalka duumada polyvalent antigen polypeptide; Tallaalka peptide peptide ee bini'aadamka papillomavirus ee kansarka makaanka afkiisa waxa uu galay tijaabada caafimaadka wajiga II. Shiinaha ayaa sidoo kale shaqo badan ka qabtay cilmi baarista noocyo kala duwan oo tallaalada polypeptide ah.

Peptides si loo ogaado cudurka

Isticmaalka ugu weyn ee peptides ee reagents ogaanshaha waa sida antigens, unugyada difaaca si loo ogaado noolaha pathogenic u dhigma. Antigens-yada polypeptide ayaa aad uga gaar ah microbial-ka ama antigens-ka borotiinka parasitic waana ay fududahay in la diyaariyo. Dib-u-hagaajinta ogaanshaha ka hortagga ee lagu ururiyay antigens-ka polypeptide 2013 waxaa ka mid ah: A, B, C, Fayraska cudurka beerka, HIV, cytomegalovirus aadanaha, fayraska herpes simplex, fayraska rubella, Treponema pallidum, cysticercosis, trypanosoma, cudurka Lyme iyo reagents ogaanshaha rheumatoid. Inta badan antigens-ka peptide-ka ee la isticmaalo waxaa laga helay borotiinka asalka ah ee jirka u dhigma, qaarna waxay ahaayeen peptides gebi ahaanba cusub oo laga helay maktabadda peptide.