Tesamorelin peptide (INN) (magaca ganacsiga Egrifta) waa nooc synthetic ee hormoonka koritaanka-hormoonka-hormoonka (GHRH) kaas oo loo isticmaalo daaweynta lipodystrophy-xiriirka HIV-ga, oo la ansixiyay bilowgii 2010. Waxaa soo saaray oo soo saaray Theratechnologies, Inc. Kanada. Daroogadu waa peptide synthetic oo ka kooban dhammaan 44 amino acids ee GHRH bini'aadamka oo lagu daro kooxda trans-3-hexenoic acid.

Tesamorelin peptide waa analog synthetic synthetic oo xasilan oo ka mid ah peptide hypothalamic, Hormoonka Koritaanka Hormoonka Hormoonka (GHRH) ee lagu tilmaamay dhimista dufanka caloosha ee xad-dhaafka ah ee bukaannada qaba HIV ee qaba lipodystrophy. Lipodystrophy waa xaalad dheef-shiid kiimikaad ah oo lagu garto caabbinta insulin, qaybinta dufanka, iyo hyperlipidemia ee la xidhiidha daaweynta antiretroviral ee caabuqa HIV.

Tesamorelin peptide waa hoormoonka sii daaya hoormoonka korriinka (GHH) analog kaas oo la muujiyay inuu kordhiyo hoormoonka koritaanka iyo heerarka IGF-1. Tesamorelin hadda waa hoormoonka ugu waxtarka badan ee sii daaya GH ee suuqa. Waa peptide la isku duro oo soo saara wax soo saarka dabiiciga ah ee HGH (Hormoonka Kobaca Aadanaha). Waxay xidhaa oo kicisaa soo-dhoweeyayaasha GHRH ee bini'aadamka oo leh awood la mid ah sida GHRHyada dabiiciga ah. Lama muujin inay si weyn u saamayso hormoonnada kale ee pituitary ee jirka.

Qanjirka 'pituitary gland'

FAA'IIDOOYINKA TESAMORELIN:

Waxay kordhisaa wax soo saarka dabiiciga ah ee HGH (hormoonka koritaanka aadanaha)

Waxay kordhisaa IGF-1 (Factor Growth Insulin-1) iyada oo aan la beddelin cabbirrada gulukooska

triglycerides oo yaraaday

Tissue Adipose Visceral Adipose (VAT)

Cabbirka Warbaahineed ee Karootid Intima oo la dhimay (cIMT)

Garashada wanaagsan ee dadka waaweyn ee ka weyn da'da 60 sano.

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