Izilondolozo zonyango ezisetyenziswa ngokuqhelekileyo zehomoni yokukhula ziyi-phenol, i-cresol kunye nokunye. I-Phenol sisilondolozi esiqhelekileyo samayeza. Uphononongo olwenziwa yi-United States Environmental Protection Agency (EPA) lubonise ukuba ukuchanabeka kwi-phenol kunokubangela ukudodobala komntwana. Kukho iimeko zokusetyenziswa esibhedlele kwe-phenol disinfectants ekhokelela ekuqhambukeni kwe-hypobilirubinemia yosana kunye nokufa komntwana, ngoko i-phenol ithathwa njengetyhefu kwiintsana okanye kwi-fetus.
Ngenxa yetyhefu ye-phenol, i-FDA, i-EU kunye ne-China zilawule ngokungqongqo umda ophezulu wokongezwa kwezinto ezigcinayo. I-FDA imisela ukuba ukuxinwa kwe-phenol kufuneka kulawulwe ngaphakathi kwe-0.3%, kodwa i-FDA iphinda ichaze ukuba iziphumo ezibi kakhulu ziye zaxelwa kwezinye izigulana nakwizigxina ezivunyelweyo, kwaye ukusetyenziswa kwexesha elide kufuneka kugwenywe. Ukuthathwa ngokuqhubekayo kweedosi eziphantsi ezivumelekileyo nako kufuneka kuthintelwe ngaphezulu kweentsuku ezili-120. Oko kukuthi, nangona i-concentration ye-phenol eyongeziweyo kwi-hormone yokukhula iphantsi kakhulu, ukusabela kwayo okungalunganga kwenzeka rhoqo emva kokusetyenziswa kwexesha elide, kwaye namatyala akhokelela kwizifo anokufumaneka kuyo yonke indawo. Emva koko, i-preservatives i-bacteriostatic yityhefu, kwaye ukuba i-toxicity iphantsi kakhulu, injongo ye-bacteriostatic ayisebenzi.
Ngenxa yeemfuno zobugcisa eziphakamileyo ze-ejenti yamanzi e-hormone yokukhula, abaninzi abavelisi bamanzi be-hormone yokukhula banokongeza kuphela izigcini zokuqinisekisa ukuba i-hormone yokukhula ayiwohloki ngenxa yetekhnoloji yokuvelisa, kodwa i-injection yexesha elide ye-preservatives iya kuzisa umonakalo onobungozi inkqubo ye-nervous central yabantwana, isibindi, izintso kunye namanye amalungu omzimba. Ngoko ke, kwizigulane ezisetyenziselwa ixesha elide le-hormone yokukhula, i-hormone yokukhula ngaphandle kokukhusela kufuneka ikhethwe ngokusemandleni, ukwenzela ukuba ugweme ngokufanelekileyo imiphumo eyingozi ye-preservatives kwaye wenze ukusetyenziswa kwexesha elide kukhuselekile kubantwana.
