Ngenxa yokuba kwingcamango yeprotheni, yonke iseli emzimbeni kunye nazo zonke izinto ezibalulekileyo zineeprotheni ezibandakanyekayo. Iiprotheyini zibalelwa kwi-16% ~ 20% yobunzima bomzimba womntu. Kukho iintlobo ezininzi zeprotheyini emzimbeni womntu, ezineempawu ezahlukeneyo kunye nemisebenzi, kodwa zonke zenziwe ngeendidi ezingama-20 ze-Amino acid ngokwemilinganiselo eyahlukeneyo, kwaye zihlala zixutywa kwaye zihlaziywa emzimbeni.

Ezi 20 amino acids emzimbeni womntu zinokudityaniswa ngokukhululekileyo kwiipeptides ezingama-2,020, inani elikhulu kakhulu. Ngokombono osisiseko wokuba isakhiwo sebhayoloji simisela umsebenzi, umgaqo-siseko wesenzo se-peptide nganye esebenzayo unzima kakhulu. Njenge-peptide ye-antibacterial anti-inflammatory, i-peptide yokulawula i-immune kwi-thymosin.

I-peptide ye-antibacterial anti-inflammatory: i-antibacterial anti-inflammatory peptide (C-L)→ intlawulo elungileyo → isenzo se-bacterial cell membrane → kwi-pathogen (efana ne-Escherichia coli) i-cell membrane drilling → i-intracellular material ukuvuza → ukufa kwebhaktheriya, oko kukuthi, ukubulala ibhaktheriya; Kwangaxeshanye, inokunciphisa i-endotoxin → ukunciphisa ukudumba okubangelwa yi-LPS.

I-Thymosin phakathi kwe-peptides ye-immunomodulatory inokuphucula ukusebenza komzimba ngokukhuthaza ukuphuhliswa kunye nokuvuthwa kwee-subsets ze-T lymphocyte, ukuphucula amandla e-phagocytosis ye-macrophages kunye nokwandisa inqanaba lokubonisa i-interleukin. Ithole i-thymosin, njengoko sihlala siyibiza njalo, ikakhulu isebenza kwinkqubo ye-T-lymphocyte ukunyusa ukusebenza kwe-cell immune system kunye nokwandisa ukuxhathisa kwizifo.

I-Il-6 yinto ye-pleiotropic, enokulawula ukukhula kunye nokuhlukana kweeseli ezahlukeneyo, ukulawula ukuphendula komzimba, ukuphendula kwesigaba esinzima kunye nomsebenzi we-hematopoietic, kwaye udlale indima ebalulekileyo kwi-anti-infection immune response.

I-LTA inokuphucula ukusebenza kwe-immune ngokubopha i-TLR4 / MD2 eyinkimbinkimbi → ukusebenza kwe-NF-кB indlela yokubonisa indlela → umsebenzi we-phagocytosis we-↑T lymphocytes kunye ne-macrophages kunye ne-immune factor (njenge-TNF-α, IL-6, IL-1β, njl.).

Isimo somzimba sabantu abahlukeneyo asifani, siya kukhokelela kwisiphumo sokuthatha i-peptide ayifani, njengokutya isidlo esinye abanye abantu batya amanqatha amaninzi, abanye abantu abatyi amanqatha.

Ngokumalunga nobudala, umphumo wabantu abadala udla ngokuba ngcono kunolutsha; Ukususela kwinqanaba lempilo, abantu abagulayo badla umphumo we-peptide. Umntu osempilweni. Ngokuphathelele ukudinwa, abantu abadiniweyo benza ngcono kunabanye; Abantu ababenziwe utyando benza ngcono ngeepeptides kunabantu abangazange benziwe utyando...

Ngenxa yokuba iipeptides zinexabiso eliphezulu lezondlo, kulula ukufunxa, ukunciphisa umthwalo wendlela yokugaya, ukukhuthaza ukuphulukiswa kwesilonda kunye neempawu ezichasene nokudinwa, ngoko kuyafana neyeza elifanelekileyo, xa abantu bekwimeko ye-physiological, bafuna iipeptides ezahlukeneyo. imisebenzi yokuhambelana.

Ngophuhliso loluntu, abantu banamhlanje bajongene neengxaki ezininzi ezinxulumene nokunciphisa iipeptides. Umzekelo, izichumisi zeekhemikhali kunye nezibulali-zinambuzane zithatha ii-enzymes ezithobisa iiproteni ekutyeni kwaye zinciphise i-exogenous enzymes. Imekobume yanamhlanje ngenxa yongcoliseko lomoya, amanzi kunye nongcoliseko lomhlaba, ukulahleka okanye ukungasebenzi kwe-enzymes emzimbeni womntu, amandla omzimba womntu wokwehlisa iiproteni abuthathaka, ukugaywa kunye nokuthotywa akukwazi ukwenziwa ngokuqhelekileyo, amathuba okufumana i-peptides iyancipha, ngoko ke umzimba womntu unqongophala kweepeptides; Imitha yale mihla ibangela ukuba umsebenzi wokhuselo lomzimba ube phantsi, ukukwazi ukwetyisa kunye nokwehlisa iiproteni kuthintelwe, inkqubo yokufunxa ayikwazi ukufunxa iiproteni ngokuqhelekileyo, kwaye amathuba okufumana iipeptides ayancipha.

Ukunqongophala kwePeptide kube yingxaki eqhelekileyo ngenxa yomonakalo omkhulu kunye nokulahleka kweepeptide emzimbeni womntu. Xa amandla omzimba womntu wokwenza iipeptides ebuthathaka kakhulu, umzimba womntu awukwazi ukuzalisa iipeptides kwangethuba, ngoko ke kuyimfuneko ukuthatha iziyobisi ukuhlangabezana neemfuno zomzimba womntu.