Abo baqhelene neepeptides bayazi ukuba i-IGF-1 ingasetyenziselwa inaliti ye-point-to-point yokukhula kwemisipha yendawo. Emva kokuqeqeshwa kwexesha elide, wonke umntu uya kuba namaqela abo abuthathaka, ngoko ke sinokukhetha ukusebenzisa indlela yokujova i-point-to-point efana ne-IGF-1 ukuphumeza ukukhula okwanelisayo kwamaqela emisipha ebuthathaka.

I-Mechano Growth Factor (MGF). Ukukhula kwe-Mechano Factor (i-Mechano Growth Factor) ifana nenguqulo ephuculweyo ye-IGF-1.

Xa sifuna i-muscle ethile ukuba yandiswe kwindawo, sivuselela ngomatshini loo misipha kunye ne-anti-resistance anaerobic exercise, kunye neqela le-muscle elivuselelwe i-ADAPTS kule ntshukumo ngokwandisa imicu ye-muscle kunye nokwandisa iiseli ze-muscle. Ngethuba le nkqubo, umzimba uvelisa iFactor Growth Factor ebizwa ngokuba yiMGF (Mechano Growth Factor). Emva kokuvuselelwa komatshini we-muscle, i-IGF-1 gene iguqulelwa kwi-MGF ukuqalisa i-myohypertrophy kunye ne-muscle fiber division kunye nokulungisa umonakalo we-muscle wendawo, ophunyezwa ngokuvula i-anabolism yeeseli ze-muscle stem. MGF kunye IGF-1 ngokwenene izinto homologous, kodwa umahluko kukuba isiphelo MGF has a C-terminal peptide.

Ngoko izihlunu ezisebenza ngokwenene zivelisa i-MGF, kwaye amaqela emisipha angasebenziyo awavelisi MGF ngeli xesha. Qaphela ukuba i-MGF idlala indima ebalulekileyo ekukhuleni kwemisipha yendawo.

Ke ngoko, ukungena kwangaphandle kwezinto ze-MGF zokukhula koomatshini kunokufikelela:

1. Lungisa iiseli ze-skeletal muscle ezonakalisiweyo kunye nokulungisa imicu yemisipha.

2. Ukubonelela ngeeseli ze-stem eziyimfuneko ekukhuleni kwemisipha yendawo ukuze kuqinisekiswe ukukhula okwaneleyo kwamaqela emisipha ekujoliswe kuyo.

I-MGF isetyenziswe kwishishini lokwakha umzimba ixesha elide, kwaye umphumo we-TA ngokwenene ukhawuleza! Ukuba yongezwa emva koqeqesho, i-MGF inokuhlawulela ngokukhawuleza ukungabikho koqeqesho kwiindawo ekujoliswe kuzo okanye ukukhula ngokukhawuleza kwamaqela angama-muscle anganelisekanga.