Unyaka ka-2021 unyaka we-100 wokutholakala kwe-insulin. Ukutholakala kwe-insulin akugcinanga nje ngokuhlehlisa isiphetho seziguli ezinesifo sikashukela ezashona ngemva kokuxilongwa, kodwa futhi kwakhuthaza ukuqonda komuntu nge-protein biosynthesis, ukwakheka kwekristalu, izifo ezizimele kanye nemithi enembile. Eminyakeni eyi-100 edlule, kube nemiklomelo emi-4 kaNobel yocwaningo nge-insulin. Manje, ngokubuyekezwa okusanda kushicilelwa ku-Nature Medicine nguCarmella Evans-Molina nabanye, sibuyekeza umlando we-insulin wekhulunyaka kanye nezinselelo esibhekana nazo esikhathini esizayo.