Ngoba kusukela emcabangweni wamaprotheni, wonke amangqamuzana omzimba nazo zonke izingxenye ezibalulekile anamaprotheni ahilelekile. Amaprotheni enza i-16% ~ 20% yesisindo somzimba womuntu. Kunezinhlobo eziningi zamaprotheni emzimbeni womuntu, anezakhiwo nemisebenzi ehlukene, kodwa wonke akhiwe izinhlobo ezingama-20 ze-amino acid ngezilinganiso ezihlukene, futhi ahlala egaywa futhi evuselelwa emzimbeni.

Lawa ma-amino acid angama-20 emzimbeni womuntu angahlanganiswa ngokukhululekile abe ngama-peptide angama-2,020, okuyinani elikhulu kakhulu. Ngokombono oyisisekelo wokuthi isakhiwo sebhayoloji sinquma umsebenzi, isimiso sesenzo se-peptide ngayinye esebenzayo siyinkimbinkimbi kakhulu. Njenge-peptide elwa namagciwane elwa nokuvuvukala, i-peptide yokulawula i-immune ku-thymosin.

I-peptide elwa nokuvuvukala: i-peptide eqeda ukuvuvukala (C-L) → icala elihle → isenzo se-bacteria cell membrane → ku-pathogen (njenge-Escherichia coli) ukugaya ulwelwesi lwamaseli → ukuvuza kwempahla ye-intracellular → ukufa kwamagciwane, okungukuthi, ukubulala amagciwane; Ngesikhathi esifanayo, inganciphisa i-endotoxin → yehlise ukuvuvukala okubangelwa i-LPS.

I-Thymosin phakathi kwama-peptides e-immunomodulatory ingathuthukisa ukusebenza kwamasosha omzimba ngokudala ukuthuthukiswa nokuvuthwa kwama-subsets e-T lymphocyte, ithuthukise ikhono le-phagocytosis lama-macrophage futhi ikhulise izinga lokukhuluma le-interleukin. I-Calf thymosin, njengoba sivame ukuyibiza, isebenza ngokuyinhloko ohlelweni lwe-T-lymphocyte ukuthuthukisa ukusebenza kwamangqamuzana omzimba omzimba futhi ithuthukise ukumelana nezifo.

I-Il-6 iyisici se-pleiotropic, esingalawula ukukhula nokuhlukaniswa kwamangqamuzana ahlukahlukene, ukulawula ukusabela komzimba, ukuphendula kwesigaba esibucayi kanye nomsebenzi we-hematopoietic, futhi ubambe iqhaza elibalulekile ekuphenduleni kokuzivikela komzimba okulwa nokutheleleka.

I-LTA ingathuthukisa ukusebenza kwamasosha omzimba ngokubopha i-TLR4/MD2 eyinkimbinkimbi → ukusebenza kwendlela yokubonisa i-NF-кB → umsebenzi we-phagocytosis we-↑T lymphocyte nama-macrophage nezici zokuzivikela (njenge-TNF-α, IL-6, IL-1β, njll.).

Isimo sokuphila kwabantu abahlukene asifani, kuzoholela emphumeleni wokuthatha i-peptide akufani, njengokudla ukudla okufanayo abanye abantu badla amafutha amaningi, abanye abantu abadli amafutha.

Ngokweminyaka yobudala, umphumela wasebekhulile ngokuvamile ungcono kunentsha; Kusukela endaweni yezempilo, abantu abagulayo badla umphumela we-peptide. Umuntu onempilo. Mayelana nokukhathala, abantu abakhathele benza kangcono kunabanye; Abantu abahlinzwe benza kangcono ngama-peptides kunabantu abangahlinzwanga...

Ngoba ama-peptide anenani eliphezulu lokudla okunomsoco, kulula ukumunca, anciphisa umthwalo wokugaya ukudla, akhuthaze ukuphulukiswa kwesilonda kanye nezici zokulwa nokukhathala, ngakho-ke kuyafana nomuthi ofanele, lapho abantu besesimweni sokuphila, badinga ama-peptide ahlukahlukene. imisebenzi ukuphelelisa.

Ngokuthuthuka komphakathi, abantu banamuhla babhekene nezinkinga eziningi ezihlobene nokunciphisa ama-peptides. Isibonelo, umanyolo wamakhemikhali nezibulala-zinambuzane zithatha ama-enzyme anciphisa amaprotheni ekudleni futhi anciphise ama-enzyme angaphandle. Imvelo yesimanje ngenxa yokungcoliswa komoya, ukungcoliswa kwamanzi nomhlabathi, ukulahleka noma ukungasebenzi kwama-enzyme emzimbeni womuntu, amandla omzimba womuntu okwehlisa amaprotheni ayancipha, ukugaya kanye nokuwohloka akukwazi ukwenziwa ngokujwayelekile, amathuba okuthola ama-peptide kuncishisiwe, ngakho-ke umzimba womuntu awunawo ama-peptide; Imisebe yesimanje yenza ukuthi umsebenzi wokuzivikela komzimba womuntu ube phansi, amandla okugaya nokwehlisa amaprotheni ayavinjelwa, uhlelo lokumunca alukwazi ukumunca amaprotheni ngendlela evamile, futhi amathuba okuthola ama-peptide ayancipha.

Ukuntuleka kwe-peptide sekuyinkinga evamile ngenxa yomonakalo omkhulu nokulahlekelwa kwama-peptide emzimbeni womuntu. Lapho amandla omzimba womuntu wokwenza ama-peptide eba buthaka kakhulu, umzimba womuntu awukwazi ukugcwalisa ama-peptide ngesikhathi, ngakho-ke kuyadingeka ukuthatha izidakamizwa ukuze uhlangabezane nezidingo zomzimba womuntu.