Ubunjiniyela bezofuzo buwumgogodla we-bioengineering yesimanje. Ubunjiniyela bezakhi zofuzo (noma ubunjiniyela bezakhi zofuzo, ubuchwepheshe bokuhlanganisa kabusha izakhi zofuzo) ukusika nokuhlanganisa izakhi zofuzo zezinto eziphilayo ezihlukene ku-vitro, ukuzixhuma ne-DNA yama-vectors (ama-plasmids, ama-phages, amagciwane), bese uwadlulisela kuma-microorganisms noma amangqamuzana ukuze ahlanganiswe, ukuze izakhi zofuzo ezidlulisiwe zivezwe kumaseli noma ama-microorganisms ukukhiqiza amaprotheni adingekayo. Impumelelo engaphezu kuka-60% ye-biotechnology igxile embonini yezemithi ukuze kuthuthukiswe imithi emisha eyisici noma ukuthuthukisa imithi yesintu, okuholele ezinguqukweni ezinkulu embonini eyenza imithi kanye nokuthuthuka ngokushesha kwemithi ye-biopharmaceuticals. I-Biopharmaceutical inqubo yokusebenzisa ubuchwepheshe be-bioengineering emkhakheni wokukhiqiza izidakamizwa, okubaluleke kakhulu ubunjiniyela bezakhi zofuzo. Okungukuthi ukusika, ukufaka, ukuxhuma kanye nokuhlanganisa kabusha i-DNA ngokusebenzisa ubuchwepheshe be-cloning kanye nobuchwepheshe bamasiko ezicubu, ukuze kutholwe imikhiqizo ye-biomedical. Izidakamizwa zebhayoloji zingamalungiselelo acushwe ngokwebhayoloji alungiselelwe nama-microorganisms, ama-parasites, ubuthi bezilwane kanye nezicubu zebhayoloji njengezinto zokuqala, kusetshenziswa izinqubo zebhayoloji noma ukuhlukaniswa nobuchwepheshe bokuhlanza, nokusebenzisa ubuchwepheshe bebhayoloji nokuhlaziya ukulawula ikhwalithi yemikhiqizo ephakathi nemikhiqizo eqediwe, kufaka phakathi imigomo, ubuthi, i-toxoid, i-serum, imikhiqizo yegazi, amalungiselelo omzimba, ama-cytokines, ama-antigen Amasosha omzimba e-Monoclonal kanye nemikhiqizo yobunjiniyela bezakhi zofuzo (imikhiqizo ye-DNA recombination, ama-in vitro diagnostic reagents), njll. Izidakamizwa zebhayoloji ezakhiwe futhi zangena esigabeni sokusetshenziswa komtholampilo zingahlukaniswa. zibe izigaba ezintathu ngokuya ngokusetshenziswa kwazo okuhlukene: izidakamizwa zobunjiniyela bezakhi zofuzo, imigomo yebhayoloji kanye nama-reagents okuxilongwa kwebhayoloji. Le mikhiqizo idlala indima ebaluleke kakhulu ekuxilongeni, ekuvimbeleni, ekulawuleni ngisho nasekuqedeni izifo ezithathelwanayo kanye nokuvikela impilo yabantu.