Ithiyori yokukhuluma ngofuzo. Amahomoni e-steroid anesisindo esincane samangqamuzana futhi ancibilika nge-lipid. Angangena kumaseli aqondiwe ngokusabalalisa noma ngokuthuthwa kwenkampani yenethiwekhi. Ngemva kokungena kumaseli, amahomoni e-steroid abophezela kuma-receptors ku-cytosol ukuze akhe ama-hormone-receptor complexes, angadlula i-allosteric translocation ngokusebenzisa ulwelwesi lwenuzi ngaphansi kwezinga lokushisa elifanele kanye nokubamba iqhaza kwe-Ca2+.
Ngemva kokungena ku-nucleus, i-hormone ibophezela kumamukeli ku-nucleus ukuze yakhe inkimbinkimbi. Le nkimbinkimbi ibophezela kumasayithi athile ku-chromatin angewona ama-histones, iqala noma ivimbele inqubo yokubhala ye-DNA kule sayithi, bese iphromotha noma ivimbele ukwakheka kwe-mRNA. Ngenxa yalokhu, iheha noma inciphise ukuhlanganiswa kwamaprotheni athile (ikakhulukazi ama-enzyme) ukuze kuzuzwe imiphumela yawo yezinto eziphilayo. I-molecule ye-hormone eyodwa ingakhiqiza izinkulungwane zama-molecule wamaprotheni, ngaleyo ndlela ifeze umsebenzi okhulisiwe wehomoni.
I-Hormone Response Ngesikhathi sokusebenza kwemisipha, amazinga amahomoni ahlukahlukene, ikakhulukazi lawo ahlanganisa ukuhlinzekwa kwamandla, ashintsha abe ngamazinga ahlukahlukene futhi athinte izinga lokuguquguquka komzimba kanye nezinga lokusebenza kwezitho ezihlukahlukene. Ukulinganisa amazinga amahomoni athile ngesikhathi nangemva kokuzivocavoca futhi ukuwaqhathanisa namanani athule kubizwa ngokuthi ukuphendula kwamahomoni ekuzilolongeni.
AMAHORMONE aphendula ngokushesha, afana ne-EPINEPHRINE, NOrepINEPHRINE, CORTISOL, kanye ne-ADRENOCORTICOTROPIN, AMAZWE NGOKUBALULEKILE KU-plasma NGOKUSHESHA NGEMVA KOKUZIVIKELA futhi afinyelela phezulu ngesikhathi esifushane.
Amahomoni asebenzayo amaphakathi, afana ne-aldosterone, i-thyroxine, ne-pressor, akhuphuka kancane futhi kancane ku-plasma ngemva kokuqala kokuzivocavoca, afinyelele inani eliphakeme phakathi nemizuzu.
Ama-hormone asabela kancane, afana ne-hormone yokukhula, i-glucagon, i-calcitonin ne-insulin, awashintshi ngokushesha ngemva kokuqala kokuzivocavoca, kodwa akhuphuka kancane ngemva kwe-30 kuya ku-40min yokuzivocavoca futhi afinyelele inani eliphakeme ngokuhamba kwesikhathi.
