Ngokusho kwephepha elisha elishicilelwe ku-Chemical Science, i-prodrug yomlomo eyakhiwe ithimba lososayensi eliholwa nguProfesa Wang Binghe eMnyangweni weKhemistry e-Georgia State University ingahlinzeka nge-carbon monoxide ukuvimbela ukulimala kwezinso ezinzima.

Nakuba igesi ye-carbon monoxide (CO) inobuthi ngemithamo emikhulu, ososayensi bathole ukuthi ingaba nemiphumela ezuzisayo ngokunciphisa ukuvuvukala nokuvikela amangqamuzana emonakalweni. Ucwaningo lwangaphambilini lufakazele ukuthi i-CO inomphumela ovikelayo ekulimaleni kwezitho ezinjengezinso, amaphaphu, umgudu wamathumbu kanye nesibindi. Eminyakeni emihlanu edlule, u-Wang nabahlanganyeli bakhe bebelokhu besebenza ekuklameni indlela ephephile yokuletha i-CO ezigulini ezingabantu ngokusebenzisa ama-prodrugs-inactive compounds okumele abhekane nenqubo yamakhemikhali emzimbeni ngaphambi kokukhulula i-ejenti ye-pharmacological esebenzayo.