I-Auxin ingasetshenziswa ukwelapha ukukhubazeka kwentuthuko okubangelwa ukuntuleka kwe-hormone yokukhula.

I-hormone yokukhula, eyaziwa nangokuthi i-hormone yokukhula komuntu (hgh), iyihomoni ye-peptide evinjelwe ukusetshenziswa kwezemidlalo futhi ivame ukusetshenziselwa ukwelapha ubuncane. Inemiphumela yokwenziwa kanye ne-metabolic eyenza ukwanda kwemisipha, ikhuthaze ukukhula kwamathambo ezinganeni nasebancane, futhi iqinise imisipha nezitho zangaphakathi. Abasubathi basebenzisa i-GH ngokungemthetho ngokuyinhloko ukwakha imisipha namandla ukuze bathole inzuzo yokuncintisana.

Ngokusho kwezincwadi, umjovo we-subcutaneous noma we-intramuscular usebenza ngokulinganayo, futhi umjovo we-subcutaneous uvame ukuletha ukugxila okuphezulu kwe-serum GH kunomjovo we-intramuscular, kodwa ukuhlushwa kwe-IGF-1 kuyafana. Ukumuncwa kwe-GH kuvame ukuhamba kancane, ukugxilisa kwe-GH ku-plasma kuvame ukuphakama emahoreni ama-3-5 ngemva kokuphathwa, nesigamu sempilo evamile samahora angu-2-3. I-GH isuswa ngesibindi nezinso, ngokushesha kubantu abadala kunasezinganeni, futhi ukuqedwa okuqondile kwe-GH engasetshenzisiwe emchameni kuncane. Izinkomba: Ukwelapha ukukhula kancane kanye nokusha okukhulu ezinganeni ezinokuntuleka kwe-hormone yokukhula okungapheli, ukwehluleka kwezinso okungapheli, kanye nesifo sika-Turner.

Kungani ukukhiqizwa kwe-hormone yokukhula komuntu kuncipha ngokuya ngeminyaka:

Izihibe zokuziphendulela zisebenza. Lapho IGF-l incipha emzimbeni, amasignali athunyelwa indlala pituitary secrete hGH ngaphezulu, futhi lokhu autogenous impendulo loop umsebenzi kunciphisa ngeminyaka.