Ososayensi bathole indlela yokulawula izakhi zofuzo eziningi kumaseli emvubelo akhiwe, okuvula umnyango wokukhiqiza okuphumelelayo nokusimeme kwemikhiqizo esekelwe ku-bio.
Ucwaningo lushicilelwe ku-Nucleic Acids Research ngabacwaningi base-DSM's Rosalind Franklin Biotechnology Centre eDelft, eNetherlands naseNyuvesi yaseBristol. Ucwaningo lukhombisa ukuthi ungawavula kanjani amandla e-CRISPR okulawula izakhi zofuzo eziningi ngasikhathi sinye.
Imvubelo ka-Baker, noma igama eliphelele elinikezwe i-Saccharomyces cerevisiae, libhekwa njengamandla amakhulu ku-biotechnology. Sekuyizinkulungwane zeminyaka, awusetshenziswanga nje kuphela ukukhiqiza isinkwa nobhiya, kodwa namuhla ungase futhi uklanywe ukukhiqiza uchungechunge lwezinye izinhlanganisela eziwusizo ezakha isisekelo semithi, izinto zokubasa, nezithasiselo zokudla. Nokho, kunzima ukufeza ukukhiqizwa okuphelele kwale mikhiqizo. Kuyadingeka ukuxhuma kabusha futhi kwandiswe inethiwekhi eyinkimbinkimbi ye-biochemical ngaphakathi kweseli ngokwethula ama-enzyme amasha nokulungisa amaleveli wokuvezwa kofuzo.