I-Triptorelin Peptide ithengiswa ngaphansi kwamagama omkhiqizo we-Decapeptyl ne-Gonapeptyl phakathi kwabanye. Kuwumuthi osebenza njenge-agonist analog ye-Gonadotropin-releasing hormone, ngaleyo ndlela inkulumo ecindezelayo ehlehlayo ye-luteinizing hormone (LH) kanye ne-follicle-stimulating hormone (FSH).

Isingeniso Somkhiqizo:

I-Triptorelin Peptide ithengiswa ngaphansi kwamagama omkhiqizo we-Decapeptyl ne-Gonapeptyl phakathi kwabanye. Kuwumuthi osebenza njenge-agonist analog ye-Gonadotropin-releasing hormone, ngaleyo ndlela inkulumo ecindezelayo ehlehlayo ye-luteinizing hormone (LH) kanye ne-follicle-stimulating hormone (FSH). Kuyi-decapeptide (pGlu-His-Trp-Ser-Tyr-D-Trp-Leu-Arg-Pro-Gly-NH2) kanye ne-gonadotropin-releasing hormone agonist (GnRH agonist) esetshenziswa njenge-acetate noma usawoti we- pamoate.

Izici:

I-Triptorelin Peptide iyi-synthetic decapeptide agonist analog ye-luteinizing hormone ekhulula i-hormone (LHRH). Inamandla amakhulu kune-LHRH engapheli, i-tritorelin icindezela ngokuguqukayo ukukhiqizwa kwe-gonadotropin. Ngemuva kokuphathwa okungapheli, okuqhubekayo, le miphumela ye-ejenti eqhubekayo iyancipha ekukhiqizeni kwe-LH ne-FSH kanye ne-testicular kanye ne-ovarian steroidogenesis. Ukugxila kwe-serum testosterone kungase kwehle kumazinga avame ukubonwa emadodeni ahlinzwe ngokuhlinzwa.

Izinkomba eziyinhloko zihlanganisa i-endometriosis, yokunciphisa ama-fibroids, umdlavuza wendlala yesinye, kanye nokwelapha ubulili obudlulele besilisa ngokuphambuka okukhulu kwezocansi. Umuthi ubuye wasetshenziswa ngaphandle kwelebuli ukubambezela ukuthomba ezigulini ezine-dysphoria yobulili.

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