Gene expression theory. Cov tshuaj steroids muaj qhov hnyav molecular me me thiab yog lipid-soluble. Lawv tuaj yeem nkag mus rau lub hom phiaj ntawm lub hlwb los ntawm kev sib kis lossis kev thauj mus los. Tom qab nkag mus rau hauv cov hlwb, cov tshuaj hormones steroid khi rau receptors hauv cytosol los tsim cov tshuaj hormone-receptor complexes, uas tuaj yeem nkag mus rau allosteric translocation los ntawm daim nyias nyias nyob rau hauv qhov kub thiab txias thiab Ca2+ kev koom tes.

Tom qab nkag mus rau hauv lub nucleus, cov tshuaj hormones khi rau lub receptor nyob rau hauv lub nucleus los tsim ib tug complex. Qhov nyuaj no khi rau cov chaw tshwj xeeb hauv chromatin uas tsis yog histones, pib lossis inhibits DNA transcription txheej txheem ntawm qhov chaw no, thiab tom qab ntawd txhawb lossis inhibits qhov tsim ntawm mRNA. Yog li ntawd, nws induces los yog txo cov synthesis ntawm tej yam proteins (feem ntau enzymes) kom ua tiav nws cov teebmeem lom. Ib qho tshuaj hormone molecule tuaj yeem tsim ntau txhiab tus protein molecules, yog li ua tiav qhov kev ua haujlwm ntawm cov tshuaj hormones.

Hormone Response Thaum lub sijhawm ua haujlwm ntawm cov leeg nqaij, cov qib ntawm ntau yam tshuaj hormones, tshwj xeeb tshaj yog cov uas txhawb nqa lub zog, hloov mus rau qib sib txawv thiab cuam tshuam rau qib metabolic ntawm lub cev thiab qib kev ua haujlwm ntawm ntau yam kabmob. Kev ntsuas cov qib ntawm qee cov tshuaj hormones thaum lub sijhawm thiab tom qab kev tawm dag zog thiab muab piv nrog cov txiaj ntsig nyob ntsiag to hu ua hormonal teb rau kev tawm dag zog.

Cov tshuaj HORMONES ceev ceev, xws li EPINEPHRINE, NOrepINEPHRINE, CORTISOL, thiab ADRENOCORTICOTROPIN, yog qhov tseem ceeb ntawm cov ntshav plasma tam sim ntawd tom qab kev tawm dag zog thiab nce siab hauv lub sijhawm luv luv.

Cov tshuaj hormones nruab nrab, xws li aldosterone, thyroxine, thiab pressor, nce qeeb thiab tsis tu ncua hauv plasma tom qab qhov pib ntawm kev tawm dag zog, ncav cuag lub ncov hauv feeb.

Cov tshuaj hormones teb qeeb, xws li kev loj hlob hormone, glucagon, calcitonin thiab insulin, tsis hloov tam sim ntawd tom qab pib qoj ib ce, tab sis maj mam nce tom qab 30 mus rau 40 feeb ntawm kev tawm dag zog thiab ncav cuag lub ncov tom qab lub sijhawm.